WebJun 17, 2024 · Zoloft (sertraline) can be taken in the morning or evening according to the prescribing information for the drug. In the clinical trials used to assess Zoloft efficacy for treating depression, both morning and … WebJan 21, 2024 · Can I take half my Zoloft in the morning and half at night? Zoloft is supposed to be taken once daily, as directed by your healthcare provider. The half life of the drug is 24 hours, so it is best to take your daily dose at one time rather than splitting it which might cause an imbalance in drug plasma concentration.
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WebApr 17, 2024 · I usually take Zoloft at night before I go to bed. In the morning I wake up feeling the effects of the antidepressant which is slightly energetic. For a while though, … WebJun 28, 2016 · Posted 6 years ago. I always take mine in the morning after breakfast (I was advised to in case they upset my stomach, but actually it's fine). Then I know "that's done" and I can forget about it for the rest of the day. I too am terrified of taking meds in case they make me feel strange which I couldn't cope with, but sertraline has been fine. trulicity e nausea
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